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武漢科斯坦生物科技有限公司

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Recombinant SARS-CoV-2(2019-nCoV) S1 Protein
瀏覽量:
產品名稱:

Recombinant SARS-CoV-2(2019-nCoV) S1 Protein

NO.
017
貨號:
CSMP02440COV
中文名稱
新冠相關蛋白
英文名詞
Recombinant SARS-CoV-2(2019-nCoV) S1 Protein
CAS號
/
產品貨號:
CSMP02440COV
貨期:
現貨
價格與訂購:
2880.00
數量
-
+
庫存:
100
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產品信息
如何訂購
產品名稱(Product name)icon
Recombinant SARS-CoV-2(2019-nCoV) S1 Protein
貨號(Catalog#)icon
CSMP02440COV
描述(description)icon
Recombinant SARS-CoV-2 S1 Protein is produced by Mammalian cells expression system and the target gene encoding Met1-Tyr695 is expressed with C-His Tag
表達系統(Expression system)icon
Mammalian cells
種屬(Species)icon
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Accession #
QHD43416.1
別名(Alternative names)icon
Spike glycoprotein,Spike protein S1(S1)
預測分子量(Predicted Molecular Mass)icon
77.23kDa
實際分子量(Actual Molecular Mass)icon
100-130kDa
純度(Purity)icon
>90% as determined by SDS-PAGE
內毒素(Endotoxin level)icon
Please contact with the lab for this information
制劑(Formulation)icon
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
運輸方式(Shipping)
icon
In general, proteins are shipped out with blue ice unless customers require otherwise.
穩定性&儲存(Stability &Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶(Reconstitution)

  Please refer to the instraction in the hard copy of COA.

應用(Application)icon
Immunogen
背景(Background)
icon
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Note
iconicon
For research use only .
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