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Research Grade Ruplizumab ( 盧利珠單抗 )
瀏覽量:
產品名稱:

Research Grade Ruplizumab ( 盧利珠單抗 )

NO.
017
貨號:
CSD00002
中文名稱
盧利珠單抗
英文名詞
Research Grade Ruplizumab
CAS號
220651-94-5
產品貨號:
CSD00002
貨期:
現貨
價格與訂購:
2480.00
數量
-
+
庫存:
100
沒有此類產品
產品信息
如何訂購
貨號(Catalog No.)icon
CSD00002
通用名INNicon
Ruplizumab
純度(Purity)icon
>95%
濃度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
內毒素(Endotoxin level)icon
Please contact with the lab for this information.
產品描述(Description)icon
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.Ruplizumab is an anti-CD40L monoclonal antibody.The binding of CD40 to its ligand,CD40L is a critical element in T cell activation.In systemic lupus erythematosus,CD40L is over-expressed on T cells, B cells and monocytes.
別名(Alternative names)icon
BG-9588,hu5c8
靶點;物種(Specificity target name;species)icon
CD40LG[Homo sapiens]
靶點背景信息(Target information)icon
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
種類(Species)icon
Humanized
受體鑒定(Receptor identification)icon
IgG1-kappa
分子量(MV)icon
145448.00 Da
CASicon
220651-94-5
存儲條件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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