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Research Grade Tocilizumab ( 托珠單抗 )
瀏覽量:
產品名稱:

Research Grade Tocilizumab ( 托珠單抗 )

NO.
014
貨號:
CSD00661
中文名稱
托珠單抗
英文名詞
Research Grade Tocilizumab
CAS號
375823-41-9
產品貨號:
CSD00661
貨期:
現貨
價格與訂購:
2480.00
數量
-
+
庫存:
10
沒有此類產品
產品信息
如何訂購
貨號(Catalog No.)icon
CSD00661
通用名INNicon
Tocilizumab
純度(Purity)icon
>95%
濃度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
內毒素(Endotoxin level)icon
Please contact with the lab for this information.
產品描述(Description)icon
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody,prevents binding of IL-6 to the IL-6R,thereby inhibiting both classic and trans-signaling.Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis.
別名(Alternative names)icon
Atlizumab,MRA/R-1569/RHPM-1/RO-4877533
靶點;物種(Specificity target name;species)icon
IL-6R
活性研究(體外/體內研究)(Activity in vitro)icon
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1-100 ng/mL; 24 hours, 48 hours) inhibits the cell proliferation (growth rate) in a dose-dependent manner, growth rate by HACM is reduced almost completely by 100 ng/mL tocilizumab.
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (0.001-10,000 μg/ml; 2 days) inhibits Ba/F3-gp130-IL-6R cell proliferation stimulated with hIL-6 with an IC50 of 13.5 ng/ml.
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1 μM; 6 hours) reduces the phosphorylation of STAT3 in vitro consistent with in vivo SAS cells.
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1-5 μM; 24 hours) significantly reduces VEGF mRNA expression in SAS cells with serum-free medium.
受體鑒定(Receptor identification)icon
IgG1
CASicon
375823-41-9
存儲條件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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