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Research Grade Adalimumab ( 阿達木單抗 )
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產品名稱:

Research Grade Adalimumab ( 阿達木單抗 )

NO.
002
貨號:
CSD00093
中文名稱
阿達木單抗
英文名詞
Research Grade Adalimumab
CAS號
331731-18-1
產品貨號:
CSD00093
貨期:
現貨
價格與訂購:
2480.00
數量
-
+
庫存:
100
沒有此類產品
產品信息
如何訂購
貨號(Catalog No.)icon
CSD00093
通用名INNicon
Adalimumab
純度(Purity)icon
>95%
濃度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
內毒素(Endotoxin level)icon
Please contact with the lab for this information.
產品描述(Description)icon
Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor 2, 3. It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA 1. This drug is frequently known as Humira. It is produced by recombinant DNA technology using a mammalian cell expression system. This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered doses 1. A new biosimilar to adalimumab, named adalimumab-adaz, was approved by the FDA on October 31, 2018. This biosimilar is known as Hyrimoz, and is a trademark of Novartis AG 9.
別名(Alternative names)icon
D2E7
靶點;物種(Specificity target name;species)icon
TNFSF2/TNF-alpha/TNFA[Homo sapiens]
活性研究(體外/體內研究)(Activity in vitro)icon
Adalimumab (anti-TNF-alpha) blocks the interaction of TNF with the p55 and p75 cell surface TNF receptors, thereby neutralising the activity of this cytokine. Through its anti-TNF actions, adalimumab reduces concentrations of matrix metalloproteases (MMP-1 and -3) and other markers of cartilage and synovium turnover, reduces of matrix metalloproteases (MMP-1 and -3) and other markers of cartilage and synovium turnover, and reduces concentrations of acute phase reactants of inflammation (C-reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) and serum cytokines (IL-1β mRNA, IL-1 receptor antagonist, IL-6).
種類(Species)icon
Homo sapiens
受體鑒定(Receptor identification)icon
IgG1-kappa
分子量(MV)icon
148000.00 Da
CASicon
331731-18-1
存儲條件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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